Abstract: Seawater has obvious resource reserve advantages compared to fresh water, and so the huge potential advantages for large-scale electrolysis of hydrogen production has been paid more attention to; but at the same time, electrolysis of seawater requires more stable and active catalysts to deal with seawater corrosion problems. Graphene-based materials are very suitable as composite supports for catalysts due to their high electrical conductivity, specific surface area, and porosity. Therefore, the review introduces the problems faced by seawater electrolysis for hydrogen production and the various catalysts performance. Among them, the advantages of catalysis of graphene-based catalysts and the methods of enhancement the catalytic performance of graphene are emphasized. Finally, the development direction of composite catalysts is prospected, hoping to provide guidance for the preparation of more efficient electrocatalysts for seawater electrolysis.